I suspect two things:
The world will be more immersive and less soulless once we can actually navigate it. It’s also the first time there’s been a swamp in GTA which is cool.
Lucia will be by far the better protagonist. The other one seems poorly written and with a voice completely mismatching the character model. I think Lucia will have more depth and her voice is more pleasant.










TBoGT was Luis, who was pretty much what VI’s male protag (Jason?) should’ve been. He actually had a personality other than just being the big badass guy.
I suspect the reason they haven’t had female protagonists before is just pure male defaultism rampant in the gaming industry. Gamers would’ve made a ton of noise in the past. Otherwise, a game with Catalina as the protagonist could’ve been really interesting.